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Sunday, July 4, 2010

How haloperidol is effective in schizophrenia ?

According to dopamine theory of schizophrenia, it occurs due to overactivity of dopaminergic neurones in the limbic area of brain. Haloperidol antagonize dopaminergic activity in brain by blocking D2 receptors in brain which are located in corpus striatum & limbic system.In this way haloperidol is effective in schizophrenia.

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