It must be able to reach the part of the human body where the infection is occurring
It should not cause the development of resistant forms of parasites
It should not produce undesirable side effects in the host such as allergic reaction, nerve damage or irritation of the kidneys and gastrointestinal tract
It should be given orally without inactivation by stomach acid, or by injection (parenterally) without binding to the blood proteins
Finally, it should have a high level of solubility in the body fluids and be possible to achieve concentrations in the tissue or blood, which are sufficiently high to inhibit or kill the infectious agent.
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