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Sunday, June 27, 2010

New emerging therapies of osteoporosis

Statins:
great interest in actions of statins unrelated to their main effect of lowering LDL
Promotes osteoclasts apoptosis
Increase osteoblast activity
Increase gene expression for BMP-2
r-PTH(recombinant PTH Teriparatide)
PTH in low and intermittent doses increase bone formation without stimulating bone resorption
Subcutaneous route 25 mg/day

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