Antidepressant drugs

Depression ,in psychiatry, a symptom of mood disorder characterized by intense feeling of loss, sadness, hopelessness, failure and rejection.
Types :
1.Reactive : 60%
2.Endogenous 20-25%
3.Bipolar 15-20%
Pathophysiology
Amine hypothesis
Due to decrease functional amine dependent synaptic transmission
Medical evidence suggest that depressive states may be connected to deficiencies in the neurotransmitters norepinephrine and Serotonin. Serotonin is often referred to as the body’s natural mood altering drug & changes in serotonin levels can quickly alter mood
Classification of antidepressant drugs
Tricyclic antidepressant
Monoamine oxidase inhibitors (MAO-AI)
Selective serotonin reuptake inhibitors (SSRI)
Atypical antidepressant