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Monday, August 24, 2009
SERM
SERM or selective estrogen receptor modulators are partial estrogen agonist in bone & cardiovascular system but an antagonist in breast & endometrium.The commonly used SERM are Tamoxifen & Raloxifen. They are used in postmenopausal osteoporosis & hormonal treatment of breat cancer. They also improve lipid profile by lowering LDL cholesterol
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