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Monday, September 20, 2010

How Transgenic animals help in research ?

Transgenic animals enable scientists to understand the role of genes in specific diseases.
By either introducing or inactivating particular genes, researchers can often for the first time discover the root causes of diseases associated with gene defects
Transgenic animals allow more effective treatments to be developed.
Transgenic animals help test the safety of new medicines and vaccines
Because transgenic models can highlight specific characteristics such as certain mechanisms involved in the formation of tumours, they can demonstrate more clearly the possible side effects of new therapies
Their use in early toxicity trials may also serve to prevent the subsequent use of a larger number of animals in the development phase
Transgenics may spare the use of higher animals
Transgenic animals can produce biological products.
It may be possible to use transgenic animals to make rare biological products for medical treatment
Human alpha-1-antitrypsin, a protein used to treat the rare genetic disorder of alpha-1-antitrypsin deficiency, is just one example

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